American movie industry mainstays Brad Pitt, Cate Blanchett, Ang Lee and Brian De Palma were among the Italian festival's top prize winners, cited from a group of 23 films in competition.
Lee won the Golden Lion for best film with "Lust, Caution" ("Sie, Jie"). The period film, set in China in the 1940s, also won best cinematography, which went to Lee's director of photography, Rodrigo Prieto.
De Palma's controversial Iraq docudrama "Redacted" won the Silver Lion; and a special jury prize was awarded to indie director Todd Haynes for his time-sweeping, free interpretation of Bob Dylan in "I'm Not There."
Blanchett won best actress for her gender-bending portrayal of Dylan in the film.
Pitt won the best actor award for his portrayal of the titular renegade outlaw in "The Assassination of Jesse James by the Coward Robert Ford."
Screenwriter Paul Laverty won the best screenplay award for "It's a Free World," directed by Ken Loach. Actor Paddy Considine, who most recently portrayed a bumbling British reporter in "The Bourne Ultimatum," won a Silver Lion for his short film "Dog Altogether."
The Venezia 64 Jury at the 64th Venice Film Festival was chaired by Zhang Yimou and comprised of Catherine Breillat, Jane Campion, Emanuele Crialese, Alejandro González Iñárritu, Ferzan Ozpetek and Paul Verhoeven.
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The Venice Film Festival began Aug. 29 and concluded tonight with the annual Golden Lion awards ceremony in Palazzo del Cinema.